Depends on the method, because cut mesquite resprouts from buds below grade. Mulching scattered-to-moderate mesquite runs $350-$1,200 per acre but needs herbicide follow-up on regrowth to be permanent; grubbing (mechanical extraction below the bud zone) prices around $150-$250/hour of excavator time or per-acre on heavy stands, and is permanent. Any quote without a regrowth plan is half a quote.